研究者发表的论文表明:首先,该疫苗毒株存在持续排毒问题,还会水平传播给其他猪只;其次,该疫苗毒株可在猪群中持续传播,并且难以在早期发现和检测到(《Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-∆I177L》一文指出,经肌内注射猪只在接种28天后依然排毒,与其接触猪只在49天后出现排毒和非洲猪瘟抗体转阳的情况,提示该弱毒株存在持续排毒和水平传播);第三,如果传播到种猪群,会损害种猪繁殖及其他生产性能。
路透社原文说的是“More than 650,000 doses of the vaccines had recently been tested on hog herds in 40 provinces,with an efficacy rate of 95%,according to the government.”,国内一些媒体错误地将其翻译为:“根据越南政府的说法,他们刚刚完成了在40个省的65万头份的测试工作,保护率达到了95%。”
查阅相关报道《What does Vietnam's ASF vaccine approval mean for the global battle?》发现,所谓95%的保护率是彻头彻尾的错误。2023年6月,猪健康信息中心的全球疾病监测报告指出,与越南CP集团合作,对545个养猪场的600544头猪进行的初步结果表明,对5958头随机选择的猪进行的样本测试达到了93.34%的技术要求。
原文(感兴趣的可以直接读一下原文):
According to the June 2023 Swine Health Information Center Global Disease Monitoring Report,AVAC ASF LIVE has shown promise in clinical trials conducted since March 2022 and has been used in some pig farms after receiving conditional distribution approval in July 2022.The report states that preliminary results on 600,544 pigs from 545 pig farms,in partnership with livestock company CP Vietnam,demonstrated 93.34%of the technical requirements as a result of sample tests on 5,958 randomly selected pigs.
8.Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-∆I177L
9.Taking a Promising Vaccine Candidate Further:Efficacy of ASFV-G-ΔMGF after Intramuscular Vaccination of Domestic Pigs and Oral Vaccination of Wild Boar